Multipotent, Pluripotent, and Totipotent Stem Cells and Induced Pluripotent Stem Cells Stem cells are undifferentiated cells that have two characteristics: they give rise to different mature cell types and have…
Keratinocytes: The Key Supporter of the Skin Barrier Keratinocytes are the most common cell type of the skin. They are present in the epidermis, which is the outermost layer of…
Endothelial Cells and the Extracellular Matrix (ECM) Endothelial cells line the vessels of the circulatory system and provide important support for vessel homeostasis, wound repair, and the inflammatory response. The…
Lifeline® Products in Research Studies in First Half of 2019 It’s that time again! Time for our mid-year review, where we look back on the last six months and review…
Small Airway Epithelial Cells The airway is lined by a layer of epithelial cells with multiple functions. In addition to providing a protective barrier function, the airway epithelium also secretes…
Function and Differentiation of Keratinocytes Keratinocytes make up the majority of cells in the epidermis, the outer layer of the skin. The progenitor cells that give rise to keratinocytes are…
Melanoma: Causes and Prevention Melanoma is a type of skin cancer that arises from melanocytes, the pigmented cell type of the skin found in the outer layer of the skin…
Structure and Remodeling of the Endometrium The uterus is lined by a specialized tissue called the endometrium, which is composed of a layer of epithelial cells and underlying stromal cells.…
Fibroblast Function in Connective Tissue Fibroblasts are the most common cell type found in connective tissue throughout the body. Their main role is to produce the extracellular matrix and collagen…
Endothelial Cells and Maintenance of Barrier Integrity Endothelial cells form the innermost layer of the blood vessels and mediate important interactions with the blood. The endothelial layer is a monolayer…
Lifeline® Renal and Bladder Cells as Normal Tissue Controls Cancer treatments are designed to selectively target cancer cells, while sparing the normal cells of the body. To design drugs with…
Stem cells are specialized cell types characterized by two properties: self-renewal and the ability to give rise to, or differentiate into, multiple cell types. Totipotent stem cells are located only…
Anatomy of the Skin, the Body’s Largest Organ The skin is the largest organ in the human body and is the largest area in contact with the external environment. In…
Lung and Airway Cells: First-Line Barriers to the Outside World Breathing air is something we do without thinking. But while we go about our day, our respiratory systems are hard…
The Female Reproductive System Every month, the female reproductive system is responsible for the maturation and of an egg from one of the two ovaries. During this time, the inner…
Smooth Muscle Cells: Involuntary Contractile Cells Smooth muscle cells (SMCs) are spindle-shaped cells found throughout the body in the walls of many organs that have contractile function. For example, in…
Endothelial and Microvascular Endothelial Cells The cardiovascular system pumps blood to every tissue in our bodies through a network of arteries, veins, and capillaries. A key component of any blood…
Fibroblasts: The Main Components of Connective Tissue Fibroblasts are specialized cells that are often identified by their spindle-like shape and expression of the protein Vimentin. They are found in connective…
Research Studies Using Lifeline Cells: 2018 Review
Anatomy of the Skin The skin is composed of three layers: epidermis, dermis, and hypodermis. The epidermis is the outermost layer of the skin and is primarily composed of keratinocytes,…
